产品货号：
Z33377
中文名称：
Beclin 1/BECN1抗体
英文名称：
Anti-Beclin 1/BECN1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Beclin 1/BECN1 Antibody |
| 指标别名 | ATG6;Beclin 1;beclin 1;autophagy related;beclin1;BECN1;GT197;Protein GT197;VPS30;Beclin-1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | BECN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Beclin 1 |
| 实际分子量 | 52～60KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Beclin-1,also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene.Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K),also named Vps34,are required for the initiation of the formation of the autophagosome in autophagy.This gene participates in the regulation of autophagy and has an important role in development,tumorigenesis,and neurodegeneration.Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagywhich in turn results in increased neuronal cell death.It has been found that beclin-1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30,and in human MCF7 breast carcinoma cells. |
| Uniprot ID | Q14457 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
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